Activation of Interferon Regulatory Factor 5 by Site Specific Phosphorylation
نویسندگان
چکیده
منابع مشابه
Activation of Interferon Regulatory Factor 5 by Site Specific Phosphorylation
The cellular defense to infection depends on accurate activation of transcription factors and expression of select innate immunity genes. Interferon regulatory factor 5 (IRF5), a risk factor for systemic lupus erythematosus, is activated in response to pathogen recognition receptor engagement and downstream effector molecules. We find the nucleotide-binding oligomerization domain containing pro...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0033098